Scientific-research work

The Department of Pharmacology conducts active research work in the following areas:

  1. Search for new highly effective and low-toxic membrane stabilizing substances among newly synthesized compounds
  2. The study of pharmacological activity and safety of new dosage forms from domestic plant materials

Employees of the department annually take part in competitions of the Ministry of Education and Science of the Republic of Kazakhstan, intra-university competitions, etc. In recent years, the following projects have been submitted to participate in the competition for grant funding of the Ministry of Education and Science of the Republic of Kazakhstan:

  1. «The role of CD4+CD25+Foxp3+Tregs in the regulation of the inflammatory process: metal-induced mechanisms of immunosuppression and the search for new methods of pathogenetic correction in the experiment». Project manager – Balabekova M. Executors – Seitaliyeva A., Amirkulova M. The deadline is 2019-2020. Funding source – KazNMU named after S.D. Asfendiyarov
  2. «Mechanisms of adaptation of cell membranes and immunity when using freeze-dried saumal in patients with hepatitis C». Project manager – MusaevAbdugani – professor of KazNMU named after S.D. Asfendiyarova. Executors – Satbayeva E., Batagoyeva Z. Terms of implementation – 2018-2020. Funding source – Ministry of Education and Science of the Kazakhstan Republic.
  3. «Study of antiarrhythmic activity of new piperidine derivatives». Project manager — Satbaeva E.M. 01.2021-12.2021 г. Competition for grant funding for scientific and (or) scientific and technical projects for 2021-2023 with a period of implementation of 12 months Ministry of Education and Science of the Kazakhstan Republic. 2021.
  4. «Modernization of medical education based on distance learning». Project manager — Satbaeva E.M. 01.2020 – 12.2021. Competition for the Global Fund for scientific and (or) scientific and technical projects for 2020-2022 with a implementation period of 12 months.
  5. «Study of the pharmacological properties of synthetic analogues of curcumin and its derivatives». Project manager — Satbaeva E.M. 2022 – 2024. Competition for grant funding for scientific and (or) scientific and technical projects for 2022-2024, Ministry of Education and Science of the Kazakhstan Republic 15.04.2022
  6. «Research and pharmacological study of new local anesthetics among piperazine derivatives». Project manager — Seytalieva A.M.. 01.2021-12.2021. Competition for grant funding for scientific and (or) scientific and technical projects for 2021-2023 with a period of implementation of 12 months, Ministry of Education and Science of the Kazakhstan Republic. 2021. Project funding approved and successfully completed.
  7. «Study of the pharmacological properties of new nitrogenous compounds». Project manager — Satbaeva E.M. 04.2021-03.2023. Competition for an intra-university grant of KazNMU 2020-2021 гг. Project funding approved.

The results of scientific research are regularly published in various scientific studies, incl. in peer-reviewed journals with an impact factor, new inventions are annually issued in the form of innovative patents of the Republic of Kazakhstan and patents of the Republic of Kazakhstan.

Over the past 3 years, 5 articles have been published in peer-reviewed journals with an impact factor indexed by SCOPUS and Web of Science, 10 articles in journals recommended by the Committee for Quality Assurance in the Sphere of Education of the Ministry of Education of the Republic of Kazakhstan and international publications. Received 5 patents of the Republic of Kazakhstan. 

Master’s dissertations were successfully defended at the Department of Pharmacology:

  • «Local anesthetic activity of new modified derivatives of trimecaine, tolperisone and diphenhydramine», Tursymbek Sh.N. 7M10104 – Biomedicine specialty (June 2, 2022)
  • «Study of the pharmacological activity of the plant extract of Artemisia Schrenkiana Ledeb», Erkenova N.B. 7M10104 – Biomedicine specialty (June 2, 2022)
  • «Pharmacological study of a new cosmetic cream based on herbal medicinal raw materials», Orazkeldy A.O. 7M10104 – Biomedicine specialty (June 2, 2022)

       Research work is carried out as part of the implementation of doctoral and master’s dissertations:

  • Khaiitova M.D. 3rd year of study PhD doctoral student 8D10103 – Medicine specialty, «Search for potential local anesthetics among new derivatives of piperidine and piperazine»
  • Serdalieva D.M. 3rd year of study PhD doctoral student 8D10103 – Medicine specialty, « Study of pharmacological properties of newly synthesized imidazole, benztriazole derivatives »
  • Nurgali A.T. 2nd year of study master’s student 7М10114- Biomedicine specialty, “Research of some types of biologically active mixtures based on plant raw materials for the fight against infections”.

The Department of Pharmacology organized various scientific events:

  • 2nd Gazi University and Asfendiyarov Kazakh National Medical University Health Sciences Congress. Republic of Kazakhstan, Almaty, KazNMU named after S.D. Asfendiyarova, May 26-27, 2022. 25 reports (oral in mixed online/offline format)
  • International Olympiad in Pharmacology 2022 among 3rd year students of the faculties “General Medicine” and “Pediatrics”. Number of teams – 13 (KazNMU named after S.Zh. Asfendiyarov, KSMA named after Akhunbaev, Al-Farabi KazNU, TashPMI, Samarkand State Medical University, Kokshetau University named after Sh. Ualikhanov, Astana Medical University.
  • Annual international student Olympiad in the section “Pharmacology” 2023 among 3rd year students. Number of teams – 19 (Volga Research Medical University, Tashkent Medical Academy, Medical University of Karaganda, Tashkent Pharmaceutical Institute, West Kazakhstan Medical University named after M. Ospanov, Samarkand State Medical University, South Kazakhstan Medical Academy, Bukhara State Medical Institute named after Abu Ali ibn Sino, Kazakh-Russian Medical University, Tashkent Pediatric Medical Institute, Kyrgyz State Medical Academy named after I.K. Akhunbaev, Termez branch of the Tashkent Medical Academy, KazNMU named after S.D. Asfendiyarov, Kyrgyz-Russian Slavic University named after Boris Yeltsin, Astana Medical University)

Employees of the department annually participate with a report in republican and international scientific conferences:

  • V Congress of Pharmacologists of Russia: “Scientific foundations for the search and creation of new drugs”, May 14-18, 2018 Yaroslavl.
  • Symposium with international participation. Biophysics of complex systems. Dubna, Russia. 27.01.2020-01.02.2020.
  • ISIUM Conference, Bangkok 2020. Bangkok, Thailand. 01.2020-28.01.2020.
  • International online conference “Science and Education: Current Issues, Achievements and Innovations in Medicine”. Republic of Uzbekistan Tashkent April 16, 2021.
  • International distance scientific and practical conference «Modern approach of experimental and preclinical pharmacology». Ukraine, Kharkov, February 19, 2021.
  • II Central Asian Congress of Clinical Pharmacology in the framework of the 90th anniversary of NJSC “KazNMU named after. D. Asfendiyarov”. Republic of Kazakhstan, Almaty, November 6, 2020.
  • 1st Gazi University and Kazakh National Medical University named after S.D. Asfendiyarov Health Sciences Congress. Türkiye, Ankara, December 1-2, 2021.
  • International Scientific and Practical Conference “Medical Science in the Era of Digital Transformation”. Russia, Kursk, 10.12.2021.
  • 2nd Gazi University and Asfendiyarov Kazakh National Medical University Health Sciences Congress. Republic of Kazakhstan, Almaty, May 26-27, 2022.
  • III International Scientific and Practical Conference of Pharmacologists “Topical issues of pharmacology: from drug development to their rational use”. Republic of Uzbekistan, Bukhara, May 19-20, 2022.